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Il personale dell'Agenzia Nutrizione effettua un'ampia e proficua attivita' di ricerca nel campo della Scienza dell'Alimentazione.

I temi di interesse sono:

  • Studi epidemiologici sul ruolo dell'alimentazione nella prevenzione delle malattie cronico-degenerative
  • Studi di intervento con preparati nutrizionali e/o nutraceutici
  • Meta-analisi e studi bibliografici su campi di interesse nel campo delle Scienze dell'Alimentazione
  • Ruolo della nutrizione nella patogenesi delle malattie cardiovascolari
  • Ruolo dell'alimentazione nell'insorgenza della Steatosi Epatica Non Alcolica
  • Attivita' fisica come strumento preventivo delle malattie cronico-degenerative

 

Principali pubblicazioni (aa. 2013-2018)

  • Pancani S, Vannetti F, SOFI F, Cecchi F, Pasquini G, Fabbri L, Mosca IE, Macchi C; Mugello Study Working Group. Association between physical activity and functional and cognitive status in nonagenarians: results from the Mugello study. Int Psychogeriatr 2018 Dec 18:1-8. doi: 10.1017/S1041610218001424.
  • Dinu M, Pagliai G, Macchi C, SOFI F. Active commuting and multiple health outcomes. A systematic review and meta-analysis. Sports Med 2018; doi: 10.1007/s40279-018-1023-0
  • Dinu M, Pagliai G, SOFI F. Alimentazione e attività fisica: il binomio per la salute. Alcologia 2018; 34: 101-106.
  • Moscarelli L, SOFI F, Mascherini G, Bini V, Ingletto C, Mandoli M, Galanti G, Stefani L. Metabolic profile and myocardial performance of renal transplant recipients participating in undersupervised physical exercise as a prescription program. J Funct Morphol Kinesiol 2018; 3: 46; doi: 10.3390/jfmk3030046
  • SOFI F, Dinu M, Pagliai G, Cei L, Sacchi G, Benedettelli S, Stefani G, Gagliardi E, Tosi P, Bocci R, Bussi B, de Santis G, Rodriguez y Hurtado I, de Kochko P, Riviere P, Carrascosa-García M, Martínez I. Health and nutrition studies related to cereal biodiversity: a participatory multi-actor literature review approach. Nutrients 2018; 10, 1207; doi:10.3390/nu10091207.
  • Sticchi E, Gisuti B, Cordisco A, Gori AM, Sereni A, SOFI F, Mori F, Colonna S, Fugazzaro MP, Pepe G, Nistri S, Marcucci R. Role of lipoprotein (a) and LPA KIV2 repeat polymorphism in bicuspid aortic valve stenosis and calcification: a proof of concept study. Intern Emerg Med 2018; doi: 10.1007/s11739-018-1925-8.
  • Minieri S, SOFI F, Mannelli F, Gatta D, Benvenuti D, Buccioni A. New trends in bioactive compounds of milk: a review of the functional activities and processing effects. SDRP J Food Sci Technol 2018; 3: 378-388.
  • Dinu M, Pagliai G, SOFI F. Response by Dinu et al to Letters Regarding Article “Low-Calorie Vegetarian Versus Mediterranean Diets for Reducing Body Weight and Improving Cardiovascular Risk Profile: CARDIVEG Study (Cardiovascular Prevention with Vegetarian Diet)”. Circulation 2018; 138: 655.
  • Longo UG, SOFI F, Dinu M, Candela V, Salvatore G, Cimmino M, Jennings JM, Denaro V. Functional performance, anthropometric parameters and contribution to team success among elite goalkeepers of the Italian “Serie A”, season 2016-2017. J Sports Med Phys Fitness 2018; doi: 10.23736/S0022-4707.18.08700-5
  • Dinu M, Pagliai G, CASINI A, SOFI F. Food groups and risk of age-related macular degeneration: a systematic review with meta-analysis. Eur J Nutr 2018; doi: 10.1007/s00394-018.1771-5
  • Stefani L, SOFI F, Magro S, Mascherini G, Petri C, Galanti G. Exercise and cancer survivors: lessons learned from a multi-facted model for exercise prescription. J Funct Morphol Kinesiol 2018; 3: 38.
  • Pagliai G, SOFI F, Vannetti F, Caiani S, Pasquini G, Molino Lova R, Cecchi F, Sorbi S, Macchi C, and the Mugello study working group. Mediterranean diet, food consumption and risk of late-life depression. J Nutr Health Aging 2018; 22: 569-574.
  • Dinu M, Whittaker A, Pagliai G, Giangrandi I, Colombini B, Gori AM, Fiorillo C, Becatti M, CASINI A, Benedettelli S, SOFI F. A Khorasan wheat-based replacement diet improves risk profile of patients with nonalcoholic fatty liver disease (NAFLD): a randomized clinical trial. J Am Coll Nutr 2018; 37: 508-514.
  • Dinu M, SOFI F. Adolescenti e cibo: attenzione alle cattive abitudini. Alcologia 2018; 32: 149-154.
  • SOFI F, Dinu M, Pagliai G, Cesari F, Gori AM, Sereni A, Becatti M, Fiorillo C, Marcucci R, CASINI A. Low-calorie vegetarian versus mediterranean diets for reducing body weight and improving cardiovascular risk profile. CARDIVEG study. Circulation 2018; 137: 1103-1113.
  • Padua L, Pasqualetti P, Coraci D, Imbimbo I, Giordani A, Loreti C, Marra C, Molino-Lova R, Pasquini G, Simonelli I, Vannetti F, Macchi C, Bonaccorsi G, Boni R, Castagnoli C, Cecchi F, Cesari F, Epifani F, Frandi R, Giusti B, Luisi MLE, Marcucci R, Paperini A, Razzolini L, SOFI F, Turcan N, Valecchi D. Gender effect on well-being of the oldest old: a survey of nonagenarians living in Tuscany: the Mugello study. Neurological Sci 2018; 39: 509-517.
  • Dinu M, Pagliai G, CASINI A, SOFI F. Mediterranean diet and multiple health outcomes: an umbrella review of meta-analyses of observational studies and randomised trials. Eur J Clin Nutr 2018; 72: 30-43.
  • Bonaccorsi G, Lorini C, Santomauro F, SOFI F, Vannetti F, Pasquini G, Macchi C, Mugello Study Group. Adherence to Mediterranean diet and nutritional status in a sample of nonagenarians. Exp Gerontol 2018; 103: 57-62.
  • Pagliai G, Dinu M, CASINI A, SOFI F. Relationship between sleep pattern and efficacy of calorie-restriced Mediterranean diet in overweight/obese subjects. Int J Food Sci Nutr 2018; 69: 93-99.
  • Cesari F, SOFI F, Molino Lova R, Vannetti F, Pasquini G, Cecchi F, Marcucci R, Gori AM, Macchi C, the Mugello Study Working Group. Aging process, adherence to Mediterranean diet and nutritional status in a large cohort of nonagenarians: effects on endothelial progenitor cells. Nutr Metab Cardiovasc Dis 2018; 28: 84-90
  • Dinu M, Whittaker A, Pagliai G, Benedettelli S, SOFI F. Ancient wheat species and human health: biochemical and clinical implications. J Nutr Biochem 2018; 52: 1-9.
  • Cecchi F, Pancani S, Vannetti F, Boni R, Castagnoli C, Paperini A, Pasquini G, SOFI F, Molino-Lova R, Macchi C and the Mugello Study Working Group. Hemoglobin concentration is associated with self‑reported disability and reduced physical performance in a community dwelling population of nonagenarians: the Mugello Study. Intern Emerg Med 2017; 12: 1167-1173
  • Becatti M, Marcucci R, Mannucci A, Gori AM, Giusti B, SOFI F, Mannini L, Cellai AP, Alessandrello Liotta A, Mugnaini M, Emmi G, Prisco D, Taddei N, Fiorillo C. Erythrocyte Membrane Fluidity Alterations in Sudden Sensorineural Hearing Loss Patients: The Role of Oxidative Stress. Thromb Haemost 2017; 117: 2334-2345.
  • Dinu M, Pagliai G, SOFI F. A heart-healthy diet: recent insights and practical recommendations. Curr Cardiol Rep 2017; 19: 95.
  • Dinu M, Abbate R, Gensini GF, CASINI A, SOFI F. Vegetarian, vegan diets and multiple health outcomes: a systematic review with meta-analysis of observational studies. Crit Rev Food Sci Nutr 2017; 17: 3640-3649.
  • Dinu M, Macchia D, Pagliai G, Gori AM, Cesari F, Marcucci R, SOFI F, CASINI A. Symptomatic efficacy of buckwheat products in non-celiac gluten sensitivity (NCGS). Asia Pac J Clin Nutr 2017; 26: 630-636.
  • Molino Lova R, SOFI F, Pasquini G, Vannetti F, Del Ry S, Vassalle C, Clerici M, Sorbi S, Macchi C. Higher uric acid serum levels are associated with better muscle function in the oldest old: results from the Mugello study. Eur J Intern Med 2017; 41: 39-43.
  • Whittaker A, Dinu M, Cesari F, Gori AM, Fiorillo C, Becatti M, CASINI A, Marcucci R, Benedettelli S, SOFI F. A khorasan wheat-based replacement diet improves risk profile of patients with type 2 diabetes mellitus (T2DM): a randomized controlled trial. Eur J Nutr 2017; 56: 1191-1200.
  • Patti G, Pengo V, Marcucci R, Cirillo P, Renda G, Santilli F, Calabrò P, De Caterina AR, Cavallari I, Ricottini E, Parato VM, Zoppellaro G, Di Gioia G, Sedati P, Cicchitti V, Davì G, Golia E, Pariggiano I, Simeone P, Abbate R, Prisco D, Zimarino M, SOFI F, Andreotti F, De Caterina R; Working Group of Thrombosis of the Italian Society of Cardiology. The left atrial appendage: from embryology to prevention of thromboembolism. Eur Heart J 2017; 38: 877-887.
  • SOFI F, Dinu M, Pagliai G, Marcucci R, CASINI A. Validation of a literature-based adherence score to Mediterranean diet: the MEDI-LITE score. Int J Food Sci Nutr 2017; 68: 757-762.
  • Sereni A, Cesari F, Gori AM, Maggini N, Marcucci R, CASINI A, SOFI F. Cardiovascular benefits from ancient grain bread consumption: findings from a double-blinded randomized crossover intervention trial. Int J Food Sci Nutr 2017; 1: 97-103.
  • Fauquet J, SOFI F, Lopez-Guimerà G, Leiva D, Shalà A, Puntì J, Sanchez-Carracedo D, CASINI A. Mediterranean diet adherence among Catalonian adolescents: socio-economic and lifestyle factors. Nutr Hosp 2016; 33: 1283-1290.
  • GIANGRANDI I, Dinu M, Pagliai G, SOFI F, CASINI A. Efficacy of Oral Supplementation with Silymarin and S-Adenosyl-L-Methionine in Patients with Non Alcoholic Fatty Liver Disease – A Pilot Study. Altern Integr Med 2016; 5: 224.
  • Petroka K, Dinu M, Hoover C, CASINI A, SOFI F. Short-term Exposure to a Mediterranean Environment Influences Attitudes and Dietary Profile in U.S. College Students: The MEDiterranean Diet in AMEricans (A-MED-AME) Pilot Study. J Am Coll Nutr 2016; 35: 621-626.
  • SOFI F, Ghiselli L, Dinu M, Whittaker A, Pagliai G, Cesari F, Fiorillo C, Becatti M, Tallarico R, CASINI A, Benedettelli S. Consumption of buckwheat products and cardiovascular risk profile: a randomized single-blinded crossover trial. J Nutr Food Sci 2016; 6: 501.
  • SOFI F, Dinu M, Pagliai G, Cesari F, Marcucci R, CASINI A. Mediterranean vs. vegetarian diet for cardiovascular disease prevention (the CARDIVEG study): study protocol for a randomized controlled trial. Trials 2016; 17: 233.
  • Strazzullo P, Cairella G, Pinto A, Bordoni A, Agnoli C, Erba D, Pellegrini N, Rossi L, Russo GL, SOFI F, Verduci E. SINU 2015 congress report. Nutr Metab Cardiovasc Dis 2016; 26: 268-270.
  • De Gaetano G, Costanzo S, Di Castelnuovo A, Badimon I, Bejko D, Alkerwi A, Chiva-Blanch G, Estruch R, La Vecchia C, Panico S, Pounis G, SOFI F, Stranges S, Trevisan M, Ursini F, Cerletti C, Donati MB, Iacoviello L. Effects of moderate beer consumption on health and disease: a consensus document. Nutr Metab Card Dis 2016; 26: 443-67.
  • Melchiorre D, Pratelli E, Torricelli E, SOFI F, Abbate R, Matucci-Cerinic M, Gensini GF, Pepe G. A group of patients with Marfan’s syndrome, who have finger and toe contractures, displays tendons’ alterations upon an ultrasound examination: are these features common among classical Marfan patients? Intern Emerg Med 2016; 11: 703-11.
  • SOFI F, Dinu M. Nutrition and prevention of chronic-degenerative disease. Agriculture and Agricultural Science Procedia 2016; 8: 713-717.
  • SOFI F, Sodi A, Franco F, Murro V, Biagini D, Miele A, Abbruzzese G, Mucciolo DP, Virgili G, Menchini U, CASINI A, Rizzo S. Dietary profile of Stargardt’s disease and Retinitis Pigmentosa: is there a role for a nutritional approach? BMC Ophthalmology 2016; 16: 13.
  • Bonaccorsi G, Santomauro F, Lorini C, Indiani L, Pellegrino E, Pasquini G, Molino-Lova R, Epifani F, Macchi C Boni R, Castagnoli C, Cecchi F, Gori A, Vannetti F, Paperini A, Turcan N, Valecchi D, SOFI F, Gensini G, Abbate R. Risk of malnutrition in a sample of nonagenarians: Specific versus classic bioelectrical impedance vector analysis. Nutrition 2016; 32: 368-74.
  • Melchiorre D, Linari S, Manetti M, Romano E, SOFI F, Matucci-Cerinic M, Carulli C, Innocenti M, Ibba-Manneschi L, Castaman G. Clinical, instrumental, serological and histological findings suggest that hemophilia B may be less severe than hemophilia A. Hematologica 2016; 101: 219-225.
  • Vazquez F, Rodger M, Carrier M, Le Gal G, Reny JL, SOFI F, Mueller T, Nagpal S, Jetty P, Gandara E. Prothrombin G20210A mutation and lower extremity peripheral arterial disease: a systematic review with meta-analysis. Eur J Vasc Endovasc Surg 2015; 50: 232-240.
  • Whittaker A, SOFI F, Luisi MLE, Rafanelli E, Fiorillo C, Becatti M, Abbate R, Gensini GF, CASINI A, Benedettelli S. An organic khorasan wheat-based replacement diet improves risk profile of patients with acute coronary syndromes: a randomized crossover trial. Nutrients 2015; 7: 3401-3415.
  • Patti G, De Caterina R, Abbate R, Andreotti F, Biasucci LM, Calabrò P, Cioni G, Davì G, Di Sciascio G, Golia E, Golino P, Malatesta G, Mangiacapra F, Marcucci R, Nusca A, Parato VM, Pengo V, Prisco D, Pulcinelli F, Renda G, Ricottini E, Ruggieri B, Santilli F, SOFI F, Zimarino M; on behalf of the Working Group on Thrombosis of the Italian Society of Cardiology. Platelet function and long-term antiplatelet therapy in women: is there a gender-specificity? A 'state-of-the-art' paper. Eur Heart J 2014; 35: 2213-23.
  • SOFI F, CASINI A. Mediterranean diet and non-alcoholic fatty liver disease: new therapeutic option around the corner? World J Gastroenterol 2014; 20: 7339-46.
  • Lippi D, SOFI F, CASINI A, Abbate R, Gensini GF. Lessons of healthy lifestyle with the Science in the Kitchen. Progr Nutr 2014; 16: 3-7.
  • Cesari F, Marcucci R, Gori AM, Burgisser C, Francini S, Roberts AT, SOFI F, Gensini GF, Abbate R, Fattirolli F. Adherence to lifestyle modifications after a cardiac rehabilitation program and endothelial progenitor cells. A six-month follow-up study. Thromb Haemost 2014; 112: 196-204.
  • SOFI F, Whittaker A, Gori AM, Cesari F, Surrenti E, Abbate R, Gensini GF, Benedettelli S, CASINI A. Effect of Triticum Turgidum subsp. Turanicum wheat on irritable bowel syndrome: a double-blinded randomised dietary intervention trial. Br J Nutr 2014; 111: 1192-9.
  • SOFI F, Cesari F, CASINI A, Macchi C, Abbate R, Gensini GF. Insomnia and risk of cardiovascular disease: a meta-analysis. Eur J Prev Cardiol 2014; 21: 57-64.
  • SOFI F, Macchi C, Abbate R, Gensini GF, CASINI A. Mediterranean diet and health status: an updated meta-analysis and a proposal for a literature-based adherence score. Public Health Nutr 2014; 17: 2769-82.
  • Ghiselli L, SOFI F, Whittaker A, Gori AM, CASINI A, Abbate R, Gensini GF, Dinelli G, Marotti I, Benedettelli S. Effetti del consumo di pasta ottenuta da una varietà antica di grano duro su parametri di rischio delle malattie cardiovascolari: uno studio di intervento. Progr Nutr 2013; 15: 265-273.
  • Molino Lova R, SOFI F, Pasquini G, Gori AM, Vannetti F, Abbate R, Gensini GF, Macchi C, for the Mugello Study Working Group. The Mugello Study, a survey of nonagenarians living in Tuscany: design, methods and participants’ general characteristics. Eur J Intern Med 2013; 24: 745-749.
  • Cioni G, Boddi M, Fatini C, Romagnuolo I, CASINI A, Gensini GF, Abbate R, SOFI F. Peripheral-arterial tonometry for assessing endothelial function in relation to dietary habits. J Invest Med 2013; 61: 867-871.
  • SOFI F, Macchi C, CASINI A. Mediterranean diet and minimizing neurodegeneration. Curr Nutr Rep 2013; 2: 75-80.
  • SOFI F, Macchi C, Abbate R, Gensini GF, CASINI A. Mediterranean diet and health. Biofactors 2013; 39: 335-342.
  • SOFI F, Abbate R, Gensini GF, CASINI A. Importance of diet on disease prevention. Int J Med Med Sci 2013; 2: 56-60.
  • SOFI F, Whittaker A, Cesari F, Gori AM, Fiorillo C, Becatti M, Marotti I, Dinelli G, CASINI A, Abbate R, Gensini GF, Benedettelli S. Characterization of Khorasan wheat (Kamut) and impact of a replacement diet on cardiovascular risk factors: cross-over dietary intervention study. Eur J Clin Nutr 2013; 67: 190-195.
  • SOFI F, Giorgi G, Cesari F, Gori AM, Mannini L, Parisi G, CASINI A, Abbate R, Gensini GF, Poli BM. The atherosclerotic risk profile is affected differently by fish flesh with a similar EPA and DHA content but different n-6/n-3 ratio. Asia Pac J Clin Nutr 2013; 22: 32-40.
  • Sodi A, Guarducci M, Vauthier L, Ioannidis AS, Pitz S, Abbruzzese G, SOFI F, Mecocci A, Miele A, Menchini U. Computer assisted evaluation of vessel tortuosity in Fabry disease. Acta Ophthalmology 2013; 91: e113-9.
  • Cesari F, Marcucci R, Gori AM, Burgisser C, Francini S, SOFI F, Gensini GF, Abbate R, Fattirolli F. Impact of a cardiac rehabilitation program and inflammatory state on endothelial progenitor cells in acute coronary syndrome patients. Int J Cardiol 2013; 167: 1854-1859.
  • Ricci I, SOFI F, Liotta AA, Fedi S, Macchi C, Pratesi G, Pulli R, Pratesi C, Abbate R, Mannini L. Alterations of haemorheological parameters in patients with peripheral arterial disease. Clin Haemorheol Microcirc 2013; 55: 271-276).